• Burr hole craniostomy versus minicraniotomy in chronic subdural hematoma: a comparative cohort study 

      Zolfaghari, Shaian; Bartek, Jiri; Strom, Isabelle; Djärf, Felix; Wong, San-San; Ståhl, Nils; Jakola, Asgeir S.; Nittby Redebrandt, Henrietta (Peer reviewed; Journal article, 2021)
      Background Chronic subdural hematoma (CSDH) is one of the most common neurosurgical diseases. In surgical management of CSDH, there is a lack of standardized guidelines concerning surgical techniques and a lack of consensus ...
    • Clinical Course in Chronic Subdural Hematoma Patients Aged 18–49 Compared to Patients 50 Years and Above: A Multicenter Study and Meta-Analysis 

      Bartek, Jiri; Sjåvik, Kristin; Dhawan, Sanjay; Sagberg, Lisa Millgård; Kristiansson, Helena; Ståhl, Fredrik; Förander, Petter; Chen, Clark C.; Jakola, Asgeir Store (Journal article; Peer reviewed, 2019)
      Objective: Chronic Subdural Hematoma (cSDH) is primarily a disease of elderly, and is rare in patients <50 years, and this may in part be related to the increased brain atrophy from 50 years of age. This fact may also ...
    • Development and external validation of a clinical prediction model for functional impairment after intracranial tumor surgery 

      Staartjes, Victor E.; Broggi, Morgan; Zattra, Costanza Maria; Vasella, Flavio; Velz, Julia; Schiavolin, Silvia; Serra, Carlo; Bartek, Jiri; Fletcher-Sandersjöö, Alexander; Förander, Petter; Kalasauskas, Darius; Renovanz, Mirjam; Ringel, Florian; Brawanski, Konstantin R.; Kerschbaumer, Johannes; Freyschlag, Christian F.; Jakola, Asgeir Store; Sjåvik, Kristin; Solheim, Ole; Schatlo, Bawarjan; Sachkova, Alexandra; Bock, Hans Christoph; Hussein, Abdelhalim; Rohde, Veit; Broekman, Marike L.D.; Nogarede, Claudine O.; Lemmens, Cynthia M.C.; Kernbach, Julius M.; Neuloh, Georg; Bozinov, Oliver; Krayenbühl, Niklaus; Sarnthein, Johannes; Ferroli, Paolo; Regli, Luca; Stienen, Martin N. (Peer reviewed; Journal article, 2021)
      OBJECTIVE Decision-making for intracranial tumor surgery requires balancing the oncological benefit against the risk for resection-related impairment. Risk estimates are commonly based on subjective experience and generalized ...
    • Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial 

      Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)
      Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ...
    • Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial 

      Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ...
    • Long-term follow up of patients with WHO grade 2 oligodendroglioma 

      Carstam, Louise; Latini, Francesco; Solheim, Ole Skeidsvoll; Bartek, Jiri; Pedersen, Lars Kjelsberg; Zetterling, Maria; Beniaminov, Stanislav; Sjåvik, Kristin; Ryttlefors, Mats; Jensdottir, Margret; Rydenhag, Bertil; Smits, Anja; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Purpose Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly evident how this glioma entity differs ...
    • Lower-Grade Gliomas: An Epidemiological Voxel-Based Analysis of Location and Proximity to Eloquent Regions 

      Gómez Vecchio, Tomás; Neimantaite, Alice; Corell, Alba; Bartek, Jiri; Jensdottir, Margret; Reinertsen, Ingerid; Solheim, Ole; Jakola, Asgeir S. (Peer reviewed; Journal article, 2021)
      Background: Glioma is the most common intra-axial tumor, and its location relative to critical areas of the brain is important for treatment decision-making. Studies often report tumor location based on anatomical taxonomy ...
    • Preoperative Prognostic Index for Patients with Brain Metastases—A Population-Based Multi-Centre Study 

      Winther, Rebecca Rootwelt; Skovlund, Eva; Andreassen, Joakim Stray; Arvidsson, Lisa; Halvardson, Jonathan; Solheim, Ole Skeidsvoll; Bartek, Jiri; Kaasa, Stein; Hjermstad, Marianne Jensen; Vik-Mo, Einar Osland (Peer reviewed; Journal article, 2023)
      Background: Brain metastases (BM) are common in cancer patients and are associated with high morbidity and mortality. Surgery is an option, but the optimal selection of patients for surgery is challenging and controversial. ...
    • Variations in the management of diffuse low-grade gliomas - A Scandinavian multicenter study 

      Munkvold, Bodil Karoline Ravn; Solheim, Ole; Bartek, Jiri; Corell, Alba; De Dios, Eddie; Gulati, Sasha; Helseth, Eirik; Holmgren, Klas; Jensdottir, Margret; Lundborg, Mina; Mireles, Eduardo Erasmo Mendoza; Mahesparan, Rupavathana; Tveiten, Øystein Vesterli; Milos, Peter; Redebrandt, Henrietta Nittby; Pedersen, Lars Kjelsberg; Ramm-Pettersen, Jon-Terje; Sjöberg, Rickard L; Sjögren, Björn; Sjåvik, Kristin; Smits, Anja; Tomasevic, Gregor; Vecchio, Tomás Gómez; Vik-Mo, Einar O.; Zetterling, Maria; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background Early extensive surgery is a cornerstone in treatment of diffuse low-grade gliomas (DLGGs), and an additional survival benefit has been demonstrated from early radiochemotherapy in selected “high-risk” patients. ...